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The 80-125% Rule: Understanding Bioequivalence Confidence Intervals in Generic Drugs

The 80-125% Rule: Understanding Bioequivalence Confidence Intervals in Generic Drugs

  • Cheryl Moran
  • January 27, 2026
  • 12 Comments

The 80-125% rule ensures generic drugs work like brand-name versions by measuring how much drug enters your bloodstream. It's not about pill strength-it's about body absorption. Here's how it works.

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